I wish I'd also added Seroquel to my post. Though it is an antipsychotic, I do think it's helped with some depression alleviation in the past. Generally if I'm in a mixed state, raising it can sometimes help. If I'm more purely depressed and very low energy, taking it but at slightly lower doses can make a difference. Most drug info websites say that doses of around 300 mg are recommended for bipolar depression. For mania, 300 mg up to 800 mg. I do think the dose can be different for different people and situations.