I've suffered from acute anxiety for 45 years and taken every medication (mostly benzos which always wear-off). I started Saphris in the hospital last month and my anxiety completely stopped! Incredible! But I'm having these horrible attacks which last over 2 hrs! I shake like crazy and can't speak. Makes it extremely hard to go out, etc. Over 2 yrs of therapy didn't help, deep breathing does nothing. When attacks go away (in the afternoon) I feel decent for once in my life!!!