I don't know much such things, but I think a second-opinion is definitely something to consider if your illnesses are interfering with your work and life and current treatments in not effective enough. Maybe I am wrong, but that is my opinion. Not sure about how your seeing another doc would affect your relationship with your current doc unless it is done secretly. Sorry I don't know how to be helpful to you. Sure hope others see your post and respond with really helpful ideas. My heart goes out to you!