My medications help a lot but are not the same as the ones you are taking. In my case, the medications are designed to slowly reverse atrophy in certain regions of my brain so they didn't show much effect until the healing was almost complete: 5 or 6 weeks. Nowadays, I am just on maintenance doses so that the atrophy does not return. What conditions are your medications used for and have you been on them long? I am so sorry that you are getting a poor response. That must be so frustrating and disheartening!