It's wonderful that you are already taking steps to help understand what your wife is going through so you can help her to the best of your ability!

In regards to your question about Zyprexa, I started taking the generic form (olanzapine) not to long ago and noticed a difference very quickly. My pdoc actually just increased my dose and I noticed an small improvement the next day. I learned the hard way that I am very sensitive to the medication though (I had major side effects at the 5 mg dose which is a pretty low dose) so it's possible this is why I am experiencing improved symptoms so quickly. I do not know enough about the medication to know how others have responded to the medication.

As others said though, it really does depend on the person. I hope your wife sees improvements soon!