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Originally Posted by BeyondtheRainbow
Thank you! While I don't think this is EPS I am having pretty significant hand tremors that my pdoc thinks are related to my clozapine. We're adjusting the dose and doing labs but I will ask her about this as it's a pretty harmless thing to try. I'd much rather try that than cogentin. I also can't take propanolol because of a low BP.
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Yes, I know about your low blood pressure.
Cogentin and other anticholinergics might be implicated in Alzheimer's disease if taken long term, my psychiatrist says. And I do not need that. I already have Alzheimer's in family history and a genetic mutation of Alzheimer's. I am trying to avoid increasing the risk. Vitamin B6 sounds innocent in comparison.
He sent me info about toxicity. It has been noticed only at levels above 1 g and only when supplementation was with pyridoxine, one of the 3 forms of Vitamin B6. And in studies of the anti-EPS effects, dosages around 300-600 mg were used. So I think we are in the clear.
I also had significant hand tremor in the past (at least as bad as what my late grandma had after the stroke in her seventies), but mine was due to Depakote. It fully resolved after I stopped Depakote.