I've been on Latuda for years. While I have only a partial response, as I do with just about everything, it does help a little with my depression.

You do have to take it with a small meal, so I take it with dinner.

It didn't cause weight gain and doesn't make me tired.

The only problem with it was that there wasn't a generic available making it really expensive, but now there's a genetic available so it might be more affordable.