It sounds like a place that my wife worked at. Even during the job interview, she was warned by the female office manager about the environment with a comment "you know how women can be." (I paraphrase.) The male boss only nodded but said, "I can't tell you that, but she can." But it's this boss's expectations of female behavior and acceptance of it that's the real problem.
And when our (autistic) daughter was just starting middle school, a girl might befriend her on Monday and refuse to be seen with her on Wednesday. That's how cliques affect girls' relationships. Even worse, a girl might pretend to be her friend but then backstab her by revealing something to other group of girls who would then taunt her about it. Maybe she was easy prey because of her autism -- too naive to be wary or on guard...
As a male, this affects me like water on a duck's back (not at all).