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Tart Cherry Jam · Dec 14, 2023 at 01:31 AM

Quote:

Originally Posted by 185329

Yeah, I haven't tried that drug. I think I am a pretty median weight person. If anything, the olanzapine helped me reach a more normal BMI; before the Zyprexa, I was borderline underweight. Now I'm about 185-190lbs at about 6'3", which puts my BMI right around 25.

Anyway, it would seem to me that Lybalvi would be rather expensive. I'm not too sure how much samidorphan would cost on its own, however. But $324.09 for a thirty-day supply (and this was back in the late nineties) seems to be very lucrative for Eli Lilly. I was surprised that it was more expensive than Clozaril.

I surmise the reason for this is that in retrospect, besides Seroquel, olanzapine was the newest antipsychotic.

You need to read up on patents, expiration of patents, and generics. Then you will understand why new drugs are expensive and why later they become cheap. Clozaril, the first atypical antipsychotic historicalaly, is much, much older than Zyprexa. Clozaril is older by decades. So of course when Zyprexa was the new kid on the block, Clozapine was probably alreaydy off patent and generics are cheap. Now you can buy generic olanzapine but there is no generic for Lybalvi which was approved, if my memory does not fail me, in 2021.