I take an antidepressant called mirtazepine at night, I does help me sleep.

You are sounding particularly agitated, it sounds like you should see a pdoc asap to discuss your options... any way to called the pdoc's office tomorrow to see whether there's been a cancellation where you could see the pdoc sooner?

Maybe the seroquel you're taking now has expired and has lost its effect? What is the dose?