Yes the constipation is Pristiq and I went to the gastroenterologist and he said the same that I might need to try another antidepressants only problem is conventional medicine doesn't work on me. Either give me problems or doesn't work at all. I'm starting to think big pharma is bad and just want to go to the naturopath. I've now used naturopathic ways to lower my cholesterol. Just sick of conventional medicine it hasn't worked for me and big pharma has injured lots of people. I just wish doctors weren't so arrogant in thinking that natural medicine is worthless. I've found more help with natural stuff then SSRIs and snris.