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Originally Posted by Nammu
Using high doses of B6 can cause toxicity. The side effects are not pleasant. I urge people not to play doctor and prescribe themselves medicine or high doses of any supplements.
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You do not need levels as high as those that cause toxicity. I take 300 mg which is near the bottom of the range reported to ameliorate EPS (250 mg and up). This is well below the toxic levels:.
"Vitamin B6 (pyridoxine) causes
neuropathy at intakes of
1000 mg per day or more, which is about 800 times the daily intake from foods"
[How much vitamin B6 is toxic?] - PubMed.
Oh, and I also take a B complex because the general B complex intake improves the safety and response to B6.
It was my psychiatrist who investigated this issue and prescribed B6 to me, and then I did my own research and learned that I also need B complex.
And this is far better than taking Cogentin which was prescribed to me years ago by other pdocs to counteract Parkinsonism as Cogentin raises the risk of Alzheimer's disease after long term use, something B6 use does not do.