Divine1966 is correct; if you drink a soda sweetened with high fructose corn syrup or the Coca-Cola brand that boasts about natural sugar, Interesting things happen for most. You will most likely drop weight, and your A1C blood value will go down significantly in some people. If it is a soda containing caffeine, some adverse effects can amount to withdrawal from the caffeine. Just one teaspoon of caffeine equals around 28-30 cups of coffee. This can cause mild irritability and nervousness; you may crave sugar and caffeine if it is a sugary soda. It can elevate your blood pressure slightly and increase your heart rate. All of these effects should pass relatively quickly. Their severity is usually proportional to your daily consumption; it can also cause headaches. If you can tolerate it and get a headache, acetaminophen is good as long as it is not contraindicated. It won't destroy your stomach like Ibuprofen does with man. They taught me a few things at Vanderbilt, after all.