Seroquel is a good medication, although some people may stop taking it without medical advice because it is very sedating and can cause clouded thinking. I never had to deal with this condition, so it is one of the few medications I am not on, but I have seen many people who were prescribed it professionally. I used to write a 30 or 90-day supply of it for them until they could see a psychiatrist if they needed it. Clozaril is also effective; I saw many people who were on that too.