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Manarinorange, do you think this is part of the agoraphobia?
I had this issue the first time I drove myself to a new school. It provoked a lot of anxiety in me. I was nauseous and skipped breakfast, plus I had dry heaves before getting into the car. This was over 40 years ago.
Today, I would use something like Google Maps "Street View" to get familiar with the area I'd be traveling to. And if I had to be there at a specific time (like for a job interview), I'd probably make a "practice trip" a few days before to rehearse the trip without the pressure of getting there at a certain time. And, I'd allow for plenty of time for the real trip so I do not have the anxiety compounded by the fear of getting there late.