I think some people are good as activity partners and some for deeper stuff. The so called best friend might be ok for activities like clubbing. Friend from the hospital clearly isn’t up to too many activities so maybe just occasional talk.

I’d also start initiate less. Let’s see if they initiate. They might be agreeing to things they don’t really care about. And they lack maturity to speak up so they just don’t show up or leave early. Sound like teenagers to me rather than adults