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raspberrytorte When I was prescribed prozac, before my diagnosis, it triggered a mixed state. I'm currently on Wellbutrin. When I first started Wellbutrin, it really helped alleviate the depression symptoms I was having. But, when I tried a dose higher than what I'm on, it gave me worse irritability than some of the types I've been hypomanic. I actually haven't tried a lot of antidepressants. My first pdoc stopped them after I was diagnosed and Wellbutrin was the first one my current pdoc suggested.