Cobenfy is the brand new antipsychotic. Right on their site first thing it says….

Do not take COBENFY if you have trouble emptying your bladder completely or at all (urinary retention problems); moderate or severe liver problems (impairment); gastric retention problems (your stomach empties slower than it should); an allergy to COBENFY, xanomeline, trospium chloride, or any of the ingredients in COBENFY; or an eye problem called untreated narrow-angle glaucoma (fluid build-up in your eye).

I have had urinary retention three times in the last couple years- twice from psych meds! No thanks!!! Plus I have fatty liver and always have raised liver enzymes! I almost had a liver biopsy because my liver enzymes shot way up a couple months ago. Sometimes I wonder what my pnurse is thinking!