When my wife had severe _nausea_ in the summer, she found out it was due to the Fentanyl patch. We think that the increased temperature caused her to absorb more medication.

Another time she was taking a pain med that starts with C (not codeine). I brought home a case of grapefruit -- a guy at work selling them to raise money for his church. That's when the trouble started. I suspected the grapefruit because I've heard it can interfere with the metabolism of meds. But no, the monograph didn't mention anything about this. So I looked up the enzyme that was needed to metabolise the med, and I saw it was the same as the one "consumed" by eating grapefruit.

In both cases, the nausea went away soon after discontinuing the meds and/or the grapefruit. And the prescribing doctor had no clue what was going on.

I wonder if the C-med was Carprofen? I keep thinking Compex...