Speaking of HRT, I can’t even have the Mirena any more never mind estrogen because I develop blood clots in my lungs! Just like 2 weeks ago! I also had had a liver biopsy and had to be off blood thinners for four days. Bam! Double blood clots ! The blood clots happened within a few days after the biopsy but I also got the Mirena iud at almost the same time.