I have recently been listening to numerous podcasts about history, particularly the history of epidemics in the past, including cholera, plague, typhus, and smallpox, among others. Learning about the devastation these epidemics brought made me realize that they, coupled with wars and famines, make my shot at life (using @NovaBlaze's expression, thank you) an event of such tiny likelihood (meaning, that all my ancestors managed to survive and reproduce) that I better make the most of it and feel grateful for what I have.