I have been on Vraylar for quite a while now- 9 months? But at 3 mg per day. Just this past Wednesday it was increased to 4.5 mg per day and in the last month I’ve gained 5 pounds but it’s been creeping up on me for a while. My BMI is now 35! 😕. It didn’t show any weight gain in clinical trials but in real life it has. It’s the last med I can take- Over the last 20 years of taking psych meds, I’ve reacted to the rest or the Genesight test said I shouldn’t take certain other meds. I’m also on Gabapentin 300. My Pdoc said if this doesn’t work out ECT is my only other option!