I hear ya on having tried a whole slew of antidepressants to no avail. I was depressed for years and probably was on every SSRI under the sun. I went to doctor after doctor since I was 7 to try and figure out the right combination of meds for me to be on, and I, at one point, ended up on 7 different meds! Still, all I got were side effects, and no positive effects. Now, at 27 years old, I came across a different approach to treating my depression with Orthomolecular Psychiatry, which basically means they help taper you off the meds, do lab work to see what your body needs, and then give you a regimen of nutrients to take. Believe me, I thought this was BS when I heard about it, but since then, I've gotten the lab tests, food allergy tests, brain chemistry tests, taken some reccommended supplements, and my depression is gone!