All the time! the medrol dosepack is actually stronger and usually worse than regular prednisone for what it's worth. The dose pack is only 4mg per tablet, and the prednisone comes in strengths from 1mg up to 20mg. If you ever have to use an oral steroid again I would try the prednisone that isn't in the dose pack. Your doctor can prescribe it in a descending dose just like the dose pack with ease. That is what my doctor does for me when I have a recurrence of my symptoms. It also helps to spread them out over the day instead of taking them all at once...