Hi Jan

First of all I'm on lamictal and I know that I was increased very slowly and it's my understanding that was an important process so it seems to me that was a significant jump. Second my doctor just increased mine and I was concerned about it and I had asked her how high can you go? She had said to me that 400 is the maximum, but for the "typical" you would only see real results at 200. Very rarely do you see any improvement after that. Thats not to say for some individual cases that after 200 patients are not being helped for some cases there are, but that is to be determined by the close supervision of the doctor.

Anyways, I noticed at the difference in how much your dosage is. So I went to the lamictal web site.

http://us.gsk.com/products/assets/us_lamictal.pdf

This is the official info about the drug. I was reading it and I came across this part, which specifically explains dosage when it comes to Bipolar Disorder.

It's on page 12

Bipolar Disorder: There were 2 studies done. In both studies patients were titrated to a target dose of 200mg of lamictal, as add-on therapy or as monotherapy, with gradual withdrawal of any pyschotropic medications during an 8- to 16- week open-label period. Overall 81% of 1,305 patients participating in the open-label period were receiving 1 or more other psychotropic medications. (didn't list them). Patients with a CGI-severity score of 3 or less maintained for at least 4 continues weeks, including at least the final week on monotherapy with lamictal, were randomized to a placebo-controlled, double-blind treatment period for up to 18months.

The primary endpoint was TIME. The modd episode could be depression, mania, hypomania, or a mixed episode.

It goes on more to explain between the two dosages that being 200mg and 400mg. And explaining that there isn't any real signifcant benefit for the higher dose. The reason that I'm pointing this out is because well my doctor had pointed this out prior to me reading it. As I read further I can find anywhere anyone on the amounts you are on. So I'm concerned. Also, it does talk about lamictal being combined with other drugs and some problems and side effects you could have. I don't know what you are on or what you are feeling. Maybe you could read this and it could be of some help to you. Hopefully.

Sorry if this was long winded.

I have had some pretty bad experiences with being aggressively treated with drugs and I can't tell you what damaging effects that had on me.

Hope you are well (((January)))

Take care
Eva

Btw if that url doesn't work go here and at the very bottom click complete prescribing information for lamictal
http://www.lamictal.com/