Thanks darkeyes. My T4 levels are reasonable but no T3.They say stress can prevent the reaction to T3. It is not possible to get them in combo here. I do think if we could get the treatment right I would at least feel a little better. In 2003 when I first went on replacement (very small dose, I have had to bring it up slowly) my weight dropped to 6 stone. I belong to Thyroid Australia &amp; while you get a lot of good advice, getting your doc to take any of that &amp; act on it is another matter. All complicated by the fact that they can not blood test me regularly, because of another health issue. Peace, Dawntreader. <font color="purple"> </font>