It does take a while to really make a difference because of the achingly slow climb to your best dose. I was up to a 200mg dose for several months before trying to conceive through IVF (another story-it didn't work), and had to go off. I can honestly say that it made an amazing difference in my life. I'm more balanced with the bipolar II swings, the OCD became more controllable, which made the anxiety calm down, too = less Ativan needed. I'm a better mother, wife, family member, and friend. hang in there