I've been trying to "work out" my dosage of straterra for over a month-- and the only time I ever feel well is if i DO NOT take the medication. Therefore, I'm not a big fan of straterra. I have taken it before bed, in the morning and in the afternoon-- and it either makes me lie awake all night and/or be extremely out of it and tired all day.
However, I am also aware that everyone reacts differently to medication-- so straterra may work well for you. My physician personally uses straterra and thinks it is a wonderful blessing...
Good luck finding the medication that is right for you.
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