Well I have had excezma and so does my daughter. I had the revolving door on my elbows and knees for years. When I was about 12...never got another breakout until I was 22, then got some breakouts all over for years and now haven't had a break out in about five years. I don't have any connection to allergies however it's supposed to be prevelant with people who have auto immune issues as I do. My daughter has asthma and there is the same links there. She never had a break out until a year ago and have not been able to get it to clear up completely since. (she's 10)