I've been on Wellbutrin XL 450mg for 3 1/2 months. The biggest side effect is not sleeping. Anyone have any experience with this med? What did you do for the not sleeping? I have to take 20mg of Ambien to get any sleep. The Wellbutrin does seem to be working. I'am also on Prozac 40mg qd, Synthroid 112mcgs qd, and Geodon 40mg bid.