((((((((((((((((( lifelesstraveled ))))))))))))))))))))

Did he actually call you a loser or did he point out that you alienate yourself from your friends? Those are two completely different things.

My suggestion is to talk to him and let him know about the depression. I had a hard time telling my hubby about mine but I was sure to point out that it wasn't his fault over and over again so it wouldn't strain our relationship.
I am sorry that you are struggling, I am sending you lots of hugs.