The FDA delayed approval of Wellbutrin originally because of several cases of seizures in young women in England with bulimia. This has never really been replicated again and the cases were found to be associated with excessive doses (over 450mg a day), previous seizures/head trauma etc. The doses we use now are less and the new Wellbutrin XL once a day dose reduces the chance of seizures even more. The fact is a number of antidepressants reduce the seizure threshold but Wellbutrin got stuck wilth (in my mind) an unfair reputation for causing them. I think the chances of Wellbutrin causing seizures is not anymore than most other antidepressants today. I probably wouldn't give a person who already has seizures Wellbutrin, but I can't find any really good reason to do so.

Seizures are most associated from low Na+ in people with diarrhea. The electrolytes lost in vomiting of most concern is potassium, as it can lead to fatal arrhythmias In an anorexic person not purging, electrolyte abnormalities are not present (only bulimics). Many things can cause seizures (stress, withdrawing from alcohol/medications) so the exact cause of your seizure will probably never be found. Several of my classmates in medical school had seizures from sleep deprivation, I know people that came off seizure drugs too fast (Neurontin) and others who have seized coming off a benzo (Klonopin). The neurologists have a saying "Everyone gets one free seizure." Which means that if a person only has one seizure in their life that is not considered enough to diagnosis them with a seizure disorder or put them on a seizure medicine. You may feel more comfortable off Wellbutrin, and that is something to consider too.