The seizure risk (the population statistics) are 0.1% at 300 mg/day, 0.6% at 450 mg/day, and 6.0% at 600 mg/day.

That's an exponential increase in risk, and the reason maximum dose levels are set where they are.

Now, how do you convert population statistics into true individual risks? You make up a list of all individual risk factors. That's the hard part. Experiencing a seizure after one year, while apparently maintaining decent weight and food intake (from your later post), does present a bit of an interpretative challenge. One can only surmise.

Strong emotional stress can briefly affect blood electrolytes, and brain activity. Anything that causes sweating, or any strong physical exertion (even without sweating), that raises blood pressure. A viral illness. Antibiotics given for a bacterial infection. Changes in renal function (potentially arising from extended anorexia). And so on. I'm trying to do the "scattergun" approach to the things that may have influenced your having a seizure. If you're looking for triggering influences, you may find something there, if you consider your circumstances at the time of the seizure.

For the breadth of different comorbid states for seizure, see:

http://professionals.epilepsy.com/se...disorders.html

On the left, you'll see expandable lists (with multiple levels of detail), showing all the known comorbid risks.

Wellbutrin reduces the amount of physiological disturbance required to trigger seizure, but blaming it for a seizure that took place so long after you went on it.....I'm hesitant to blame it entirely for what happened.

As you've gone off the drug, I guess analyzing it to death is moot. But looking at those risk factors, in the context of your knowledge about your own health, might lead you to consider a specific risk for further monitoring or examination.

Lar