I'm on wellbutrin, abilify and effexor. the abilify for me is for schizophrenia related illness but i have major depression too so thought it would help with that. it has made me really tired and fat. I've gained sixty pounds in a year! and now no matter what i do the weight won't come off. Overall though i think abilify is a good drug, it's just i must be overly sensitive to the side effects.