Yes, Seroquel does come in 50mg tablets. I don't see how you would be able to break a 100mg tablet into 4 pieces without crumbling it, its so tiny as it is. I just want to add that I think, as far as meds go, this is a good one. At least it has been for me. I'm not a regular med taker. I prefer to ride my bp bareback. But in a pinch, this one gives me what I need. Hope it's working out for you.
TgrsPurr.