i'm going to add my two-cents worth here. i lost 38 lbs on EffexorXR..i am five feet tall..i looked anorexic. when i started tapering, in about 30 hours, i had an appetite. i was eating every two or three days while taking the full dose of it. now i'm on depakote and lamictal and small dose of elavil. i am hungry all the time and i really watch what i eat...i am gaining..i've put on about 15 lbs in a very short time. i eat veggies, grains, tofu smoothies, whole wheat bread and am vigilant against "fatty" foods...but i still gain........i'm going to go back to walking as soon as my knee allows it. 4 miles a day and we'll see what happens. i also think that women gain easier than men.