I changed careers, sort of, from computer programming. that is, i got laid off and went to grad school in a different field.

but although I mostly enjoyed getting my BS CS, i didn't much like being a professional programmer so I probably would have done it anyway.
I say "sort of" because although I'm a grad student now, a lot of what I do still involves data processing that is a lot easier since I have the skills (databases, programming and concepts). It's a huge advantage over other people in my program.
What about programming do you want to get away from? I remember it being very isolating and lonely, and often frustrating with business demands. but it paid good and programming makes you feel powerful.