I just realized you asked about Pristiq and I never responded. It's a new anti-depressent on the market. I used to take cymbalta before that. I don't know how well it worked for me. I felt ok, but you know, not great. Then I got off my meds and became depressed, and moved into a better environment, got back on my meds and switched from cymbalta to pristiq, and things rapidly improved. It's difficult to say it was the Pristiq that is responsible all by itself, because a few different factors are involved, but I can say I haven't felt this good in a while.