I take provigil and have been taking it for about eight months. I love it! It seems to boost my anti-depressant (cymbalta) and gives me this kind of positive, constructive energy. I was the first patient my md gave it to, but he really hasn't had too much success with it with other patients. With me, it wore off after three or four months, but when he boosted it to 400 mg qd all the positive effects came back. I've been sick with depression and PTSD for seven years and this med-combo with the provigil has enabled me to go back to college. So, all the best of luck!