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There are a few interactions, but with total thyroid replacement, the process is individualized anyway.

Whatever the drugs might do to affect thyroid hormone metabolism will be stable inside your body, if the dose of those drugs is stable. You will have to be carefully titrated onto thyroid hormones (probably with a number of blood draws, over a number of weeks). So long as you keep taking the same psych drugs at the same doses, they're not going to change anything about the titration process. You'll get to the right thyroid level via the same means.

Down the road, if you change psych meds, it may conceivably require some planning. Carbamazepine, phenytoin, and sertraline all have some possible interactions with levothyroxine (T4).....but not in every person, even still.

Good luck with this. It can be a bit of a bumpy road at times.

Lar

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Thank you Larry for quick response. I had my fingers crossed that you or Cam would take the time to answer my question. I do see my pdoc this evening and will mention it. Although my blood work for thyroid function came back normal, the size of the mass in my thyroid is too large and needs to be taken out .... Thanks again!