Lithium has been great for my BP, it seems to balance things out to a happy medium. I still get a bit hypo-manic, but I'm still on my base dose (getting titrated next week). Right now I'm battling against going into a major depressive state (well, you know why LOL). And I am actually losing weight with the Lithium (yay!) even though I am on Seroquel as well.

Depakote didn't work for me, but it may work for you.

Both meds are very effective on BP and cycling, but Lithium is the most proven (as far as my research has told me) in treating rapid-cycling. But, I'm no doctor, I just play one at teatime with my stuffed animals.

Jenn