As someone that has suffered from PMDD for over five years I can tell you that the difference for me was that I wanted (and tried) to kill my self one week out of every month - I dreaded my monthly as I knew (felt) that I may not be living before the week was out.

I now take Celexa for my Mood Swings & PMDD and it has been a life saver for me.....
Sarafem is also good for PMDD.

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Mayo Clinic:
http://mayoclinic.com/health/pmdd/AN01372
(click on all links)