In my opinion anybody who has a good response to Provigil needs to be evaluated for ADHD too. ADHD folks will get some improvement in symptoms with Provigil, though it is a very, very expensive alternative to Ritalin (methylphenidate) which is probably a better, safer alternative to use in lethargic depression. Methamphetamine addicts especially raise the chance of co-occuring ADHD in my opinion.