Hi KMK!
i am going thru the same stage myself..trust me its not easy, specially if you are dealing with mental issues as well, anyways, i am a 40 y/o woman, and dealing with doctors because all of them want to give me all kinds of treatments, and most of them didint do what they were supposed to do, so, i started reading a LOT, searching on the internet, and trying to monitor my symptoms..i use a progesterone cream at night, its wonderful, its called progesta-care-plus, and i have been feeling somewhat better, i do yoga, take vitamin-supplements, keep my pm appointments, as well as my therapys, get acupunture, massages, take my medications (AD)have hobbies, etc, now its not that easy,everyday its a struggle, but, your wife needs to be willing to do it..mostly for those kids, they are watching how their mom is behaving, in a way its not her fault, but its her responsbility to seek help, anywhere, friends, family, church, counseling, etc..good luck!