I have the same questions you do about losing weight after going off Zyprexa but I have an additional question which is can one lose weight while on it with exercise and a low-calorie eating plan. I have been taking it on and off for a few years and have gained 30 lbs. while on it and I am at my wits end. My problem is that each time I go off it my anxiety spins off the charts. Just today somebody asked me if I was pregnant (like the 3rd person this school year). I have gone from 150 lbs. to 180 lbs. and am only 5'5". My advice is that if you can go off it, then do it now before you can't live without it (like me). You have been on it for such a short while that it will probably wash out of your system pretty quickly.