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Default Dec 22, 2021 at 05:47 AM
  #661
Well I tested negative by lateral flow this morning, I got quite excited but when I held it up to the lamp I got see a very faint line on the T so not quite but probably tomorrow. This matters because our isolation is now potentially reduced for vaccinated people from 10 days to 7 if a person tests negative on day 6 and 7. Hmm. I was still testing positive on day 7 so it wouldn’t have helped me, I’m playing it safe and staying home today, I’m on day 9 so not long now. I haven’t really missed going out because although I had mild symptoms (no respiratory effects at all no temperature even) I have been very tired - it’s like my body has been working hard.

@InkyTinks I had AstraZeneca 2x too and didn’t yet get my booster as for my age they kept saying 6 months then by the time they brought it to 3 months I could only bring it forward 3 days and then I had covid anyway (I work in a supermarket where I have been exposed to coughing frequently by the public so I’m fairly high risk for catching). I read of a man who had difficulty obtaining a 3rd dose of AZ as they are using MRNA for boosters, he did eventually get it - like you he couldn’t have an MRNA. Could you maybe talk to your Dr first about it?

I have to say all the breakthrough cases I’ve known were 2xAZ including myself but maybe a 3rd dose would help? I also read today AZ are working on an Omicron specific vaccine Steps taken to target Omicron with AstraZeneca jab, scientist says | Coronavirus | The Guardian

I got my blood antibody result back and I did have antibodies and was told they couldn’t be from the recent infection but were from either previous infection or vaccinations. Not sure what to make of that, it looks like I had antibodies just not enough to resist the virus? Or maybe I’ve had Omicron?

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Default Dec 22, 2021 at 06:51 AM
  #662
Maybe that's why I'm having to wait so long then if the standard dose they are giving out is Pfizer!


It's nearly xmas day now anyway and I'll be having a few drinks so best to wait until after then I can make sure I get chance to make antibodies.


I'm glad it wasn't too bad for you and you're feeling better
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Default Dec 22, 2021 at 08:48 AM
  #663
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Originally Posted by Discombobulated View Post
Well I tested negative by lateral flow this morning, I got quite excited but when I held it up to the lamp I got see a very faint line on the T so not quite but probably tomorrow. This matters because our isolation is now potentially reduced for vaccinated people from 10 days to 7 if a person tests negative on day 6 and 7. Hmm. I was still testing positive on day 7 so it wouldn’t have helped me, I’m playing it safe and staying home today, I’m on day 9 so not long now. I haven’t really missed going out because although I had mild symptoms (no respiratory effects at all no temperature even) I have been very tired - it’s like my body has been working hard.

@InkyTinks I had AstraZeneca 2x too and didn’t yet get my booster as for my age they kept saying 6 months then by the time they brought it to 3 months I could only bring it forward 3 days and then I had covid anyway (I work in a supermarket where I have been exposed to coughing frequently by the public so I’m fairly high risk for catching). I read of a man who had difficulty obtaining a 3rd dose of AZ as they are using MRNA for boosters, he did eventually get it - like you he couldn’t have an MRNA. Could you maybe talk to your Dr first about it?

I have to say all the breakthrough cases I’ve known were 2xAZ including myself but maybe a 3rd dose would help? I also read today AZ are working on an Omicron specific vaccine Steps taken to target Omicron with AstraZeneca jab, scientist says | Coronavirus | The Guardian

I got my blood antibody result back and I did have antibodies and was told they couldn’t be from the recent infection but were from either previous infection or vaccinations. Not sure what to make of that, it looks like I had antibodies just not enough to resist the virus? Or maybe I’ve had Omicron?
Certain rapid tests may not work for the omicron variant. I'd look into that. You may have a different strain.

Also, if the line is faint, you're still somewhat infectious. It's best to protect others by just quarantining an extra 3 days, and that's once all your symptoms have been gone. If you still have symptoms, even if you test negative, you should still quarantine, since it is also possible that you have been concurrently infected with a different respiratory illness at the same time. The key here is to slow the spread and make it safe for others, including yourself. There have been people who have been reinfected with omicron after first being infected with a different strain. If you have a different strain, which is likely because tests may not pick up omicron yet, then you are still at risk for getting omicron. That's what the latest data suggest. It's better to err on the side of caution instead of incurring more risk. It's this pandemic fatigue that affects our own risk assessments, especially when working with others in enclosed spaces, being around other vulnerable people, and living with one more persons.

Here's one link regarding omicron not being detectable by tests: FDA finds 3 COVID-19 tests that fail to detect the omicron variant | MedTech Dive.

And here's another link regarding omicron likely to reinfect; there's no natural immunity against omicron: Omicron more likely to reinfect than Delta, no milder -study | Reuters

Be safe.
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Default Dec 22, 2021 at 10:18 AM
  #664
I'm so glad you are feeling better @Discombobulated! Very interesting about the antibodies, I don't know what to make of that either.
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Default Dec 22, 2021 at 11:18 AM
  #665
What is this PEG?



I was told to get AZ to start with cos Pfizer was triggering severe allergic reactions due to PEG. I've been told today there are no half doses (Booster) of AZ but if Pfizer wasn't safe for me at the beginning why will it be now???



I told them I'm not risking allergic reaction and hospital just a couple of days before xmas and refused it. They're going to find out if Moderna will be any safer and contact me after xmas...does that also contain this PEG? anyone know??
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Default Dec 22, 2021 at 12:54 PM
  #666
Both Moderna and Pfizer have PEG (polyethylene glycol). It's a chemical used in a lot of cosmetics and other household products. Miralax is polyethylene gylcol.
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Default Dec 22, 2021 at 04:21 PM
  #667
Allergies and Covid-19 Vaccines:

Quote:
If You Are Allergic to Polyethylene Glycol (PEG) or Polysorbate
PEG and polysorbate are closely related to each other. PEG is an ingredient in the mRNA vaccines, and polysorbate is an ingredient in the J&J/Janssen vaccine.

If you are allergic to PEG, you should not get an mRNA COVID-19 vaccine. Ask your doctor if you can get the J&J/Janssen vaccine.

If you are allergic to polysorbate, you should not get the J&J/Janssen COVID-19 vaccine. Ask your doctor if you can get an mRNA COVID-19 vaccine.

If You Are Allergic to Other Types of Vaccines
If you have had an immediate allergic reaction—even if it was not severe—to a vaccine or injectable therapy for another disease, ask your doctor if you should get a COVID-19 vaccine. Your doctor will help you decide if it is safe for you to get vaccinated.

If You Have Allergies Not Related to Vaccines
CDC recommends that people get vaccinated even if they have a history of severe allergic reactions not related to vaccines or injectable medications—such as food, pet, venom, environmental, or latex allergies. People with a history of allergies to oral medications or a family history of severe allergic reactions may also get vaccinated.
See CDC link above. Last Updated Dec. 14, 2021
Content source: National Center for Immunization and Respiratory Diseases (NCIRD), Division of Viral Diseases
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Default Dec 22, 2021 at 04:30 PM
  #668
I've had a severe anaphylactic reaction to Ibuprofen in the past and PEG is listed in the ingredients

"The solubility of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), is enhanced by synthesizing ibuprofen ester with a water-soluble polymer, poly(ethylene glycol) (PEG)"












Inactive ingredients: carnauba wax, colloidal silicon dioxide, croscarmellose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, polydextrose, polyethylene glycol, polysorbate, titanium dioxide









From Govt site



"If you have had a severe allergic reaction or an immediate allergic reaction—even if it was not severe—to any ingredient in an mRNA COVID-19 vaccine, you should not get either of the currently available mRNA COVID-19 vaccines (Pfizer-BioNTech and Moderna)"

PEG and Polysorbate are closely related to each other. PEG is an ingredient in the mRNA vaccines, and Polysorbate is an ingredient in the J&J/Janssen vaccine.

This only leaves AZ for me!
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Help Dec 22, 2021 at 04:31 PM
  #669
AstraZeneca:

"The Polysorbate containing AstraZeneca COVID-19 vaccine is tolerated by polyethylene glycol (PEG) allergic patients":

Quote:
Abstract
Background: Polyethylene glycol (PEG) is the excipient found in the mRNA COVID-19 vaccines. We previously demonstrated PEG allergy was a cause of severe anaphylaxis to the Pfizer/BioNTech COVID-19 vaccine. PEG is widely used in many household products, cosmetics and medicines. However PEG allergy is rare, there have been few confirmed cases of PEG allergy. The excipient of potential concern in the AstraZeneca COVID-19 vaccine is polysorbate 80 (PS80). Cross-reactivity between PEG and polysorbate has been suggested, based on their composition and skin-test data. The aim of this study was to determine whether PEG-allergic patients could be vaccinated with the PS80 containing AstraZeneca COVID-19 vaccine.

Method: Eight patients with PEG allergy were identified by the allergy clinic at Cambridge University Hospital. Patients underwent skin prick testing to PS80 (20%) and to the AstraZeneca COVID-19 vaccine prior to vaccination.

Results: All eight patients allergic to PEG tolerated the AstraZeneca COVID-19 vaccine, even in 2 patients where the PS80 skin prick test was positive and 1 with a positive skin prick test to the AstraZeneca COVID-19 vaccine.

Conclusion: Patients allergic to PEG, previously denied COVID vaccination, may now be safely vaccinated with the PS80 containing AstraZeneca vaccine and need only avoid the PEG-containing mRNA COVID-19 vaccines. This opens up the possibility that these patients will also tolerate other vaccines containing PS80 such as the Janssen/Johnson and Johnson COVID-19 vaccine. Clinical cross-reactivity between PEG and PS80 did not occur in this vaccine setting.

Keywords: COVID-19; COVID-19 vaccines; PEG allergy; drug allergy; polysorbate 80.
Sellaturay P, Gurugama P, Harper V, Dymond T, Ewan P, Nasser S. The Polysorbate containing AstraZeneca COVID-19 vaccine is tolerated by polyethylene glycol (PEG) allergic patients. Clin Exp Allergy. 2021 Nov 25. doi: 10.1111/cea.14064. Epub ahead of print. PMID: 34822190.

If you're in a country that allows for this, great. If you're in the U.S., you'll need to travel abroad (which is highly unlikely, due to international requirements for both the initial vaccine(s) and the booster) to get the AZ vaccine.

NOTE: AZ vaccines and boosters wane at 3 months; every 6 months is not enough. This is what makes this drug more expensive, and probably one of many reasons why the U.S. decided not to get it.

Unfortunately, the AZ booster may NOT work against omicron; for those with allergic reactions to mRNA vaccines, they will need to mask, social distance, isolate, only go out for essentials, keep airflow purified, and clean surfaces in order to remain as safe as possible. There are no allergy-friendly vaccines to protect against omicron at this time, though getting a booster will help with the other variants and severe disease. Unfortunately, those with allergies are also high-risk for severe Covid-19 and death, so there aren't many studies on whether alternative vaccines will help protect against omicron for the immunocompromised and those with allergies to mRNA vaccine ingredients.

And, there's still some debate on whether omicron is less severe, more severe, or about the same as delta; for now, the scientists are saying that omicron might be the SAME SEVERITY AS DELTA until more data are gathered and more statistical tests are analyzed.

Quote:
...But an important preprint was released yesterday describing Omicron hospitalizations in South Africa. There was a lot in this paper, but, to me, the following was the biggest finding: Once someone got to the hospital, the odds of disease becoming severe was the same as Delta. So if the immune system was breached, Omicron did the same damage as Delta. This is consistent with another robust analysis of hospitalizations from the UK that found Omicron is not less severe than Delta.

On the other hand, lab data is showing that there are certainly physiological differences between Omicron and Delta disease processes (go here for more great details). It will be weeks or months until data crystallizes and we have a clear picture of Omicron severity. What all this means for hospitalizations and deaths in places like the United States remains unknown.
Overall, when looking at the MIXED FINDINGS across the globe, which has more integrity than politically-laden studies in individual countries and their research institutions, we will find the need to be cautious and diligent about going back to double-masking (N95 or N99 if you can), sheltering-in-place if you are high-risk or live with high-risk persons, only traveling for essentials, abiding by mandates and lockdowns, keeping airflow purified with hepa filtration and fresh air, washing hands for at least 40 seconds, keeping surfaces clean and disinfected, social distancing at least 6 feet both indoors and outdoors, avoiding indoors with unvaccinated or public areas, avoiding crowds, and getting vaccinated/boosted as recommended by your specific region's healthcare departments and/or your doctor.

The problem about spreading this virus occurs not only when your pandemic-fatigued defenses are down, but also when disinformation spreads, misinformation spreads, and/or people downplaying the severity of novel mutations. It's better to err on the side of caution than to deal with the tragic costs of medical traumas, grief/loss traumas, increased disease and disability, overwhelmed hospitals (which affects more than Covid patients), and a prolonged pandemic.

Last edited by SprinkL3; Dec 22, 2021 at 04:53 PM..
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Default Dec 22, 2021 at 05:21 PM
  #670
Thanks for the info.

I'm not in the US and I had the first 2 AZ vaccinations without any allergic reaction so I already know that one is safe for me personally.


In my country they are giving some CEV people a 3rd primary (full) dose then a booster later so I asked why I couldn't get another AZ full dose if there's no half doses.


If they don't reply I'll try again on Monday after xmas


Our govt rules say if a patient has ever had a severe reaction to ingredients in mRNA vaccines then they should be given one of the others.



Not sure what other options I have?


Anyway I'm off to bed its nearly 10.30pm here and I need to be out early with the dog when it's quiet.
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Heart Dec 22, 2021 at 05:24 PM
  #671
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Originally Posted by InkyTinks View Post
Thanks for the info.

I'm not in the US and I had the first 2 AZ vaccinations without any allergic reaction so I already know that one is safe for me personally.

In my country they are giving some CEV people a 3rd primary (full) dose then a booster later so I asked why I couldn't get another AZ full dose if there's no half doses.

If they don't reply I'll try again on Monday after xmas

Our govt rules say if a patient has ever had a severe reaction to ingredients in mRNA vaccines then they should be given one of the others.

Not sure what other options I have?

Anyway I'm off to bed its nearly 10.30pm here and I need to be out early with the dog when it's quiet.
I hope you are able to get boosted soon. I know you've been waiting for a while to get boosted. I'm so sorry you are struggling with all this - the allergies, the pandemic, this new omicron, and everything else. All this sucks! I wished it were over for all of us.

You're doing the best you can with all that you've got. I hope you have good rest and a better outlook tomorrow.
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Default Dec 22, 2021 at 08:05 PM
  #672
Everyone! Check this out! I’m absolutely shocked absolutely shocked.

N.J. reports nearly 10,000 COVID cases, the highest number yet since the pandemic started - nj.com

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Help Dec 23, 2021 at 06:34 AM
  #673
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Everyone! Check this out! I’m absolutely shocked absolutely shocked.

N.J. reports nearly 10,000 COVID cases, the highest number yet since the pandemic started - nj.com

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I'm so sorry - that's a lot of numbers! I hope the hospitals are still doing okay.

I wished that there were ways for people to report their at-home tests, and then for them to differentiate at-home tests from workplace/institutional rapid tests from antigen tests from PCR tests, and to remind us all on every coronavirus data site what those tests are, how accurate they are, and how they remove any possible "double-counts" (when a person gets an at-home test followed by a hospital-based test), so that disinformation and misinformation do not spread. The free tests are going to require some sort of logging somewhere, and that's if people are willing to share their positive or negative test results to reveal a better estimate of test positivity.

Meanwhile, it would be good to know about people's symptoms and what prompted them to take the tests - whether it be required for travel (international or domestic), required for a job because they remain unvaccinated/unboosted, due to symptoms, due to local events such as gathering with friends or attending a concert, due to weekly testing to be safe for self and/or the community, or out of pure curiosity/other reason. Negative test reporting is important because then it shows a more accurate test positivity rate, especially for those who chose to take the test because they were symptomatic. For those who take the test on a weekly basis due to their unvaccination status, it would also reveal test positivity for that particular group, when compared to those who are vaccinated; reporting of those tests should also be mandated by the companies that are required to test them when they allow their unvaccinated employees to continue working there (especially in places like meat packing warehouses, hospitals, psychology firms, research firms, food warehouses, manufacturing warehouses, dental offices, and otherwise; there really should have been mandates for those working in services with regular close contact with customers, such as in restaurants, bars, beauty salons, dental offices, psychological offices, and more, because they often don't have 100 employees, but they are nonetheless the superspreading areas that are most likely to community spread the virus).

There's a lot more we can do to reduce the spread, even without mandates. That is to get vaccinated, including boosted; wear masks whenever you leave the home; isolate those within the home who have the virus or any other illness; get tested regularly (weekly or when symptomatic); keep the air purified and recirculated with fresh air; keep hands and surfaces cleaned; avoid crowds and indoor spaces; eat outside or at home; meet people outdoors and do more outdoor activities; reduce travel to only essentials or travel safely while getting tested many times before, during, and after your trip; quarantine/isolate if you are symptomatic with any respiratory symptoms and/or fever; avoid unvaccinated persons as much as possible; set boundaries with everyone - including both vaccinated and unvaccinated persons; safeguard the vulnerable among you (such as those who are obese, older adults >40, those who are disabled, those who have a high-risk condition) by ensuring as safe environment as possible when meeting with them in-person.

The sad thing is that they are telling anyone high-risk to just stay home; that's the latest recommendation in the newspapers. The problem with that statement is increased stigma, discrimination, and hate for those who are elderly, greater than 40, overweight, obese, disabled, mentally ill, diabetic, and otherwise high-risk; people will tell them that they should be the ones to just stay home while the more able-bodied younglings can be free to go maskless, vaccineless, and do what they want. Meanwhile, the benefit of vaccines is also for the freedoms of high-risk people, not solely to remove clogged hospitals.

Most of the clogged hospitals are from unvaccinated, high-risk persons who didn't adhere to safety protocols. If they had gotten vaccinated, they could have had their health, which is a part of their freedom. But when you get sick, you lose your freedom anyway. Vaccines help freedom for all, not just for high-risk persons, though many of the antivaxxing high-risk and moderate-risk persons are the ones clogging up hospitals, not the vaccinated. So the vaccinated should feel free to enjoy their freedoms as much as the healthy ones who get vaccinated out of both their own health/safety as well as their civic duty to help others.
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Default Dec 23, 2021 at 07:41 AM
  #674
10k in NJ is shocking. I'm just waiting for it to come here. We are still getting nailed by Delta.
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Default Dec 23, 2021 at 08:06 AM
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we might be going back in to lockdown by new year's eve. the prime minister has said that he won't do it over christmas

I don't know how to feel about it really- starting the new year the same way we started this year..... and last.....

but hey: at least my life isn't on hold, I guess

it's just **** like always
 
 
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Default Dec 23, 2021 at 08:11 AM
  #676
I wish our country would go on lockdown. Freedom has its price, and that includes increased violent crimes, sedition, treason, hate, murder, superspreading events, clogged ERs, overwhelmed ICUs, deaths, lack of graveyard spaces, resentments, civil uprisings, riots, protests, civil unrest, polarization, divisions, stigma, discrimination, segregation, cheating, isolating, fears, judgments, discord, dissention, lies, healthcare crises, mutations, arguments, breakups, and more.
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Default Dec 23, 2021 at 06:14 PM
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10k in NJ is shocking. I'm just waiting for it to come here. We are still getting nailed by Delta.

It’s the highest numbers ever had ever during this pandemic

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Heart Dec 23, 2021 at 07:37 PM
  #678
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It’s the highest numbers ever had ever during this pandemic
I'm so sorry to hear about these horrible numbers, Sarah! (((safe hugs and prayers)))
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Default Dec 23, 2021 at 08:48 PM
  #679
@Discombobulated - I hope you are feeling better and are able to have a speedy recovery and are able to go out again soon. I hope your friends and husband and loved ones remain free from the virus, too.
I've been struggling lately because a friend of mine in a different state has Covid, though he refuses to get tested, but the symptoms seem like Covid. Anyway, I just worry about a lot these days, so it comes out in my posts on this pandemic.

I hope you are doing well though. I don't think I've seen posts from you lately, so I just wanted to check in. (((safe hugs)))
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Default Dec 24, 2021 at 01:31 AM
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I don't particularly want a lockdown but with so much talk about how another lockdown is most likely coming, I wish they'd just get it over with.
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