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BeyondtheRainbow
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Default Jun 08, 2021 at 10:06 PM
  #1
I'm having weird muscle cramps in my hands, feet, legs and oddly today in my side when I bent over for something. I've also had muscle twitches in my had. The only med change recently was increasing my topamax to 50 mg and that went back to 37.5 mg today.

I am scared that this is my AP. I've had this happen on APs before. I don't think it's a common side effect for clozapine (doesn't seem to be from what I've read).

I'm not sure if this is worth bugging my pdoc about. I "see' her in 3 weeks so I think I'll wait and observe. I'm just concerned because I have history of sensitivity to EPS symptoms and it's not unheard of on clozapine. Going off clozapine is just not something I can stan to to think about. I know cogentin probably will fix it but it's hard to think that any deviation from clozapine's effective is possible. I've been out of the hospital for 5 1/2 years and I prefer to keep it that way

Any opinions?

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Default Jun 09, 2021 at 02:06 AM
  #2
Hi BeyondtheRainbow. What you describe does sound concerning, especially since you state you've experienced similar in the past. I suppose if it was all from antipsychotics in the past, that would be my guess, too. I hope it will pass, but please do let your pdoc know about this, especially if it persists for another couple days. I wouldn't want to have to wait three weeks straight with such symptoms.

A couple antipsychotics that didn't give me certain side effects initially, did over time. I, like you, have also read that Clozaril has a low incidence of EPS compared to many others, but EPS does still appear in its side effect list.
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Default Jun 09, 2021 at 12:25 PM
  #3
It's probably the Clozaril causing the muscle cramping. Cogentin would likely help - but why do you say the Cogentin would cause the Clozaril to be less effective?

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Default Jun 09, 2021 at 04:13 PM
  #4
Oh, I didn't mean cogentin would make the clozaril less effective. I meant that I'm afraid of anything that would change the clozaril dose or make me have to come off it it. I didn't word it very well.

Thanks for the answers.

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