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Old Jun 12, 2013, 12:04 PM
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Mack2 Mack2 is offline
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Ebselen a safe lithium mimetic for bipolar disorder - an article from the Churchill and Sharp groups
In this article based on funding from the BBSRC we present evidence that ebselen works like lithium in mouse models of bipolar disorder. Both ebselen and lithium inhibit the same key signalling pathway to quiet overactive neurones. As ebselen has been in late stage clinical trials (Phase 3) for stroke, it has clinical safety and few side effects. Taking a known drug and using it for a new disease is termed repurposing and can dramatically reduce the time and cost of drug development. For ebselen, this means testing in man will occur within the next year by the lead author, Nisha Singh in collaboration with Professor Phil Cowen in Psychiatry.

Oxford Press Release: New drug for bipolar disorder may offer fewer side effects - University of Oxford
The article: http://www.nature.com/ncomms/journal...comms2320.html
Thanks for this!
Darth Bane

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  #2  
Old Jun 12, 2013, 01:28 PM
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intergalactictraveler intergalactictraveler is offline
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Read about it, too, with great interest. BUT, the clinical trials are going to be in the UK and maybe other EU nations. We have to deal with the Federal Dipstick Administration and they could order their own Phase 3 trials, setting things back for another year or two. Hope I'm wrong and they just let it on through. Just remember, the NSA is listening to us and monitoring our Internet activities to keep us safe from ourselves.
  #3  
Old Jun 12, 2013, 01:37 PM
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Mack2 Mack2 is offline
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I'm in Scotland but we NEVER get what the bloody English get!
  #4  
Old Jun 12, 2013, 01:56 PM
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intergalactictraveler intergalactictraveler is offline
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Soon, I hope, Scotland will be independent and you can tell the Crown where to stick it.
  #5  
Old Jun 12, 2013, 02:23 PM
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Darth Bane Darth Bane is offline
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that will be great news. lithium has bad side effects especially kidney damage. i am currently non-medicated but i would be happy to try this new thing. it's tiresome to fight bipolar without help of meds... it might turn out to be false hope though.. i shouldn't be too hopeful...
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