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Magnate
Member Since Mar 2021
Location: California
Posts: 2,685
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May 05, 2024 at 05:39 PM
#1
I can't find my old post about using high doses of Vit B6 to ameliorate EPS. I wanted to update that this has been working surprisingly well for me since last fall.
So let me start a new post and link to this 2018 article: Effect of Vitamin B6 Versus Propranolol on Antipsychotic-Induced Akathisia: A pilot Comparative Double-blind Study - PMC And this is especially important for those of us who either organically tend to low blood pressure or have AP-induced orthostatic hypotension and thus are prevented from using Propranalol. __________________ Bipolar I w/psychotic features Last inpatient stay in 2018 Geodon 40 mg Seroquel 75 mg Lybalvi 5 mg as a PRN Gabapentin 1200 mg, Vitamin B-complex (against extrapyramidal side effects) Long term side effects from medications some of them discontinued: - hypothyroidism - obesity Suspected narcolepsy Treated with Ritalin 5mg |
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Crone
Member Since May 2010
Location: Some where between my inner mind and the solar system.
Posts: 71,670
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May 05, 2024 at 05:56 PM
#2
Using high doses of B6 can cause toxicity. The side effects are not pleasant. I urge people not to play doctor and prescribe themselves medicine or high doses of any supplements.
__________________ Nammu …Beyond a wholesome discipline, be gentle with yourself. You are a child of the universe no less than the trees and the stars; you have a right to be here. …... Desiderata Max Ehrmann |
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Member
Member Since Jul 2021
Location: virginia
Posts: 246
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May 05, 2024 at 07:13 PM
#3
Im glad its working but be careful
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Magnate
Member Since Mar 2021
Location: California
Posts: 2,685
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May 05, 2024 at 08:40 PM
#4
Quote:
"Vitamin B6 (pyridoxine) causes neuropathy at intakes of 1000 mg per day or more, which is about 800 times the daily intake from foods" [How much vitamin B6 is toxic?] - PubMed. Oh, and I also take a B complex because the general B complex intake improves the safety and response to B6. It was my psychiatrist who investigated this issue and prescribed B6 to me, and then I did my own research and learned that I also need B complex. And this is far better than taking Cogentin which was prescribed to me years ago by other pdocs to counteract Parkinsonism as Cogentin raises the risk of Alzheimer's disease after long term use, something B6 use does not do. __________________ Bipolar I w/psychotic features Last inpatient stay in 2018 Geodon 40 mg Seroquel 75 mg Lybalvi 5 mg as a PRN Gabapentin 1200 mg, Vitamin B-complex (against extrapyramidal side effects) Long term side effects from medications some of them discontinued: - hypothyroidism - obesity Suspected narcolepsy Treated with Ritalin 5mg |
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Monster on the Hill
Member Since Sep 2020
Location: by the river
Posts: 4,392
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May 05, 2024 at 08:45 PM
#5
I don't know, man. Last time I was inpatient I was ready to rip my limbs off my akathisia was so bad. They put me on propranolol, a B complex vitamin, and a B6 supplement. Yeah, my vit. B levels were low at first (why the vits), but even after discharge I still wanted to go ballistic from the akathisia. Only thing that stopped it was stopping the AP (I know, not a viable option for most and even in my case it was out of not having anyone to prescribe it, but it's been a few months and I still breathe).
__________________ Live life for nothing but that sweet sweet melody. |
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Magnate
Member Since Mar 2021
Location: California
Posts: 2,685
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3 1,205 hugs
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May 05, 2024 at 10:41 PM
#6
Quote:
It took some time for B6/B complex to work consistently. At first, it was like oh great, oh no, oh great again, oh no. Now, half a year later, I do not have EPS. Granted, my doses of APs are fairly low these days. EPS usually are dose-dependent. But I do get how you would want to rip your limbs. I screamed from akathisia. __________________ Bipolar I w/psychotic features Last inpatient stay in 2018 Geodon 40 mg Seroquel 75 mg Lybalvi 5 mg as a PRN Gabapentin 1200 mg, Vitamin B-complex (against extrapyramidal side effects) Long term side effects from medications some of them discontinued: - hypothyroidism - obesity Suspected narcolepsy Treated with Ritalin 5mg |
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Legendary
Member Since Oct 2004
Location: usa
Posts: 11,217
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May 06, 2024 at 03:51 PM
#7
I had akathesia both time i was on risperdal and felt like i was gonna lose m mind it was awful!! only thing that helped was taking requip with it
__________________ Bipolar 1 w/psychotic features or schizoaffective bipolar type PTSD generalized anxiety OCD celexa, prazosin, Lybalvi and prn zyprexa and klonopin |
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