[imad]

If you have suffered a major devastating depression and have taken medication that has really helped and without serious and awful side effects, please share your wisdom.
Best wishes for those living in hell.

[bluekoi]

imad, Hello and welcome to PsychCentral.

The medication, Cymbalta, I am currently on has been the most effective for me with no side-effects.

We have many forums which may be of interest to you. A good place to start would be the links below. Browse through what other members have written and post when you feel comfortable.

Depression - Forums at Psych Central

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[Clara22]

In the past Prozac helped me, now I am not treating my depression. I have been avoiding any kind of doctors for a while. Recently I started with physical medicine

[Altered Moment]

Hello and welcome to PC.

Twenty years of meds and various other forms of treatment so it is a long complicated story. I have had limited success with meds. Some times they work ok sometimes not at all. The ones that work pretty good all ways poop out. Meaning they quit working.

After twenty years the meds I am currently on have worked far better than anything in the past but I am afraid the Fetzima is starting to poop after only 5 months. I usually get one to two years out of them. I am considered very treatment resistant though. I am right now increasing the dose. Well starting Monday as I just went to the pharmacy and they are out until Monday.

As far as side effects I am very lucky. I have very few and they go away. Two that are very common and I have had with all of them is disturbed sleep, vivid dreams, and the sexual ones. Fetzima seems to be better for me with those two.

Everyone is different though and you have to try and see what happens is the way it goes. I knew a guy on Prozac for twenty years and he swears it has saved his life and has always worked great. I don't know his current situation.

[imad]

Originally Posted by zinco14532323

Hello and welcome to PC.

Twenty years of meds and various other forms of treatment so it is a long complicated story. I have had limited success with meds. Some times they work ok sometimes not at all. The ones that work pretty good all ways poop out. Meaning they quit working.

After twenty years the meds I am currently on have worked far better than anything in the past but I am afraid the Fetzima is starting to poop after only 5 months. I usually get one to two years out of them. I am considered very treatment resistant though. I am right now increasing the dose. Well starting Monday as I just went to the pharmacy and they are out until Monday.

As far as side effects I am very lucky. I have very few and they go away. Two that are very common and I have had with all of them is disturbed sleep, vivid dreams, and the sexual ones. Fetzima seems to be better for me with those two.

Everyone is different though and you have to try and see what happens is the way it goes. I knew a guy on Prozac for twenty years and he swears it has saved his life and has always worked great. I don't know his current situation.

Same here. Similar story. Last drug I was prescribed, last week, was Mirtazapine. List of side effects is as long as my arm. It included: lethargy, tremor, confusion, nightmares and HALLUCINATIONS! I've decided to take the bull by the horns and avoid drugs. May be, after all, I don't need to take anything for depression.
I will rely on wisdom and patience, above all, on God.

[imad]

Thanks for everyone who has offered his/ her support.

[TheOriginalMe]

I'm on Agomelatine (Valdoxan), virtually no side effects. It hasn't got my mood back to where I want, but it has lifted me off the floor. I think as a long-term fix this will be a good med, but I think I need a kickstart with something else to get me right. Don't know what that something else will be, I don't tolerate the usual SSRI/SNRIs.

Sorry for the ramble, but in answer to your question, Valdoxan is worth a try.

[imad]

Originally Posted by TheOriginalMe

I'm on Agomelatine (Valdoxan), virtually no side effects. It hasn't got my mood back to where I want, but it has lifted me off the floor. I think as a long-term fix this will be a good med, but I think I need a kickstart with something else to get me right. Don't know what that something else will be, I don't tolerate the usual SSRI/SNRIs.

Sorry for the ramble, but in answer to your question, Valdoxan is worth a try.

Thanks for responding.